United States securities and exchange commission logo September 15, 2022 Tie Li Chief Financial Officer Li Auto, Inc. 11 Wenliang Street Shunyi District , Beijing 101399 People s Republic of China Re: Li Auto, Inc. Form 20-F for the Year Ended December 31, 2021 Filed April 19, 2022 Response dated August 26, 2022 File No. 001-39407 Dear Mr. Li: We have reviewed your August 26, 2022 response to our comment letter and have the following comment. In our comment, we may ask you to provide us with information so we may better understand your disclosure. Please respond to this comment within ten business days by providing the requested information or advise us as soon as possible when you will respond. If you do not believe our comment applies to your facts and circumstances, please tell us why in your response. After reviewing your response to this comment, we may have additional comments. Form 20-F for the Year Ended December 31, 2021 Part I General, page 1 1. We note that your auditor, PricewaterhouseCoopers Zhong Tian LLP, is headquartered in China. We also note that on August 26, 2022, the PCAOB signed a Statement of Protocol with the China Securities Regulatory Commission and the Ministry of Finance of the PRC to allow the PCAOB to inspect and investigate completely registered public accounting firms headquartered in China and Hong Kong, consistent with the HFCAA, and that under the agreement, the PCAOB will be required to reassess its determinations by the end of 2022. In future filings please ensure that your disclosure reflects the current regulatory landscape related to the Statement of Protocol, whether your auditor is subject to the PCAOB s reassessed determinations, and whether and how the HFCAA and related Tie Li Li Auto, Inc. September 15, 2022 Page 2 regulations will affect your company. You may contact Ernest Greene, Staff Accountant at 202-551-3733 or Kevin Stertzel, Staff Accountant at 202-551-3723 if you have questions. FirstName LastNameTie Li Sincerely, Comapany NameLi Auto, Inc. Division of Corporation Finance September 15, 2022 Page 2 Office of Manufacturing FirstName LastName